MINIMALLY INVASIVE ASSESSMENT OF IGE MEDIATED ALLERGY

Inventors

  • Prof. Yousef Haik

United Arab Emirates University
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Allergy is a major cause of severe health effects(respiratory distress, shock) throughout mankind. The most severe and life threatening reactions to foods are associated with immunoglobulin E (IgE) mediated hypersensitivity.

The current major approaches used in the diagnosis of allergies (skin test or skin prick test, assays of serum IgE levels, Histamine release test) have some drawbacks: false negative or false positive results, low sensitivity, and highly invasive nature.

The invention is about a rapid detection technique that assesses the presence of allergy indicators in a body fluid such as blood serum or saliva with high accuracy. The system makes use of a class of nanoparticles that can be treated to capture the allergy indicators, even if they are present in traces only.

Then in a second step it is also capable of detecting the concentration of such indicators by using a simple device which is similar to that utilized for glucose detection for diabetic patients.

Distinctive elements:

  • Rapid detection of allergy indicators with an easy to use device
  • Enabling end users to instantly detect the presence of allergic ingredients in e.g. food.

Examples of areas of application:

  • Allergy Diagnostics
  • Prophylactic screening