Allergy is a major cause of severe health effects(respiratory distress, shock) throughout mankind. The most severe and life threatening reactions to foods are associated with immunoglobulin E (IgE) mediated hypersensitivity.
The current major approaches used in the diagnosis of allergies (skin test or skin prick test, assays of serum IgE levels, Histamine release test) have some drawbacks: false negative or false positive results, low sensitivity, and highly invasive nature.
The invention is about a rapid detection technique that assesses the presence of allergy indicators in a body fluid such as blood serum or saliva with high accuracy. The system makes use of a class of nanoparticles that can be treated to capture the allergy indicators, even if they are present in traces only.
Then in a second step it is also capable of detecting the concentration of such indicators by using a simple device which is similar to that utilized for glucose detection for diabetic patients.